Surveillance of Vaccine Preventable Invasive Bacterial Disease (VP-IBD) in Bangladesh

VP-IBD: Funded by World Health Organization


This study has been ongoing since 2008 at 4 sentinel sites and one population-based site with the objective to collect data on vaccine-preventable invasive bacterial diseases. This is being used to measure the impact of Hib and Pneumococcus vaccine

Project Summary:

Invasive Bacterial diseases (IBD) in Culture of sterile fluids like blood and CSF are essential to diagnose any of these diseases. In Bangladesh, like other developing countries, blood and cerebrospinal fluid specimens are not collected for culture routinely, so the importance of IBD are not well appreciated in these parts of the world. However, it is known that most of the 9 million child deaths are occurring in developing countries and a vast majority can be prevented by the available highly effective vaccines. The scarcity of data on vaccine-preventable diseases is hindering the evidence-based decisions on introduction vaccine in the developing countries including Bangladesh. To remove the barrier, specifically for invasive pneumococcal diseases, GAVI’s Pneumo-ADIP conducted surveillance in Bangladesh for pneumococcal disease burden with the network of 7 hospitals from 2004 to 2008. This surveillance provided significant contribution in measuring the disease burden of Pneumococcus. In addition, the surveillance also revealed the burden of other organisms, like Haemophilusinfluenzae type b (Hib), Neisseria meningitidis, Salmonella typhi, S. paratryphi etc(6). Considering the need of active surveillance for invasive bacterial diseases, with specific attention to vaccine preventable diseases, WHO is supporting the continuation of active hospital based surveillance in 3 hospital sites of Bangladesh since 2009.