Diagnostic test is an important tool to identify the cause of infectious disease by demonstrating the presence, absence or evidence of previous existence of pathogens. To make it more useful, tools must be precise, simple and affordable for the people where it is required. Although the evolution of technologies offered us rapid tests with increased sensitivity and specificity that hold promise for the improved management and control of infectious diseases, there are several factors that can influence the performance of tests in different settings. These include geographical variances of population or organism, test methodology-manual or automatic, local diagnostic practice and skills. Therefore, wherever possible, test evaluations should be performed under the range of conditions in which they are likely to be used in practice. In some situations, such evaluations can be facilitated through multi-center trials. However, limited resources limit the ability of many developing countries to perform adequate evaluations of diagnostic tests. CHRF is providing its effort to establish rational and useful tools to improve diagnostics since decade, to help to avoid the financial and human costs associated with incorrect diagnoses, which can include poor patient care, unnecessary complications, suffering and, in some circumstances, even death.In the course of improved diagnostic, we contributed significantly to improve the detection of meningitis cases. Currently we are working to evaluate the detection system of Salmonella typhi.
What? We are conducting active laboratory-based surveillance and well-designed epidemiological surveys to guide decision-making by public health officials for disease prevention and control programs of typhoid fever. The aim of this project is to develop a new ... Read More »